WHY DO EVENT DRIVEN MICROSCOPY? In a conventional microscopy study the researcher defines an experimental configuration, typically a combination of time-lapse, z-stack, multi-channel, multi-position and multi-view settings. Importantly, everything the microscope will do is fully defined before...
Light sheet fluorescence microscopy (or SPIM – selective plane illumination microscopy) was named Nature’s Method of the Year. As demonstrated in the figure below, SPIM achieves optical sectioning by illuminating the sample with a thin sheet of light allowing the entire field of view to be...
Among the 3D cell culture methods, multicellular tumor spheroids (MCTS) generated from cancer cells are attracting models to investigate the influence of malignant cell-interactions on cellular proliferation, differentiation, apoptosis and gene expression. While growing, MCTS display a gradient...
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